ZO Skin Health

ZO Skin Health Peptide Facial Refining Concentrate

Four-peptide sculpting concentrate — smooths lines, lifts, restores volume.

Selected by Dr Chris
Hero actives
Acetyl Octapeptide-3, Acetyl Hexapeptide-8, Volumising Tripeptide, ZPOLY Complex
When & how much
AM · PM · 30 ml
£252.00/ 30 ml

Not sure if this fits your routine? Take the two-minute Skincare Quiz and Dr Chris will recommend the right products for your skin.

How to use

Where it fits in your routine

Apply 1–2 pumps morning and evening, after cleansing and before moisturiser and SPF. Smooth across the face, focusing on areas of expression lines and volume loss; extend to the neck if you wish.

Alcohol- and fragrance-free, and suitable for daily, long-term use across most skin types. A 30 ml bottle lasts around a month at the recommended amount.

Designed to be used on its own or to complement in-clinic treatments such as anti-wrinkle injections, dermal filler, Profhilo and polynucleotides — not a substitute for them. Best introduced as part of a personalised plan following a skin consultation.
What's inside

Ingredients and mechanism

Acetyl Octapeptide-3 — neuropeptide that helps modulate the appearance of dynamic expression lines, particularly the forehead and eye area.
Acetyl Hexapeptide-8 — works in synergy to smooth the look of deeper dynamic and static wrinkles and support the skin's natural collagen.
Refining Peptide Complex (Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine, Palmitoyl Dipeptide-5 Diaminohydroxybutyrate) — supports a visibly more refined, lifted, sculpted-looking facial contour.
Volumising Tripeptide (Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate) — supports the skin's natural hyaluronic acid for fuller, plumper-looking skin.
ZPOLY™ Complex — blend of four polysaccharide extracts that reduces visible redness and supports the skin barrier.

INCI: Water, Glycerin, Propanediol, Acetyl Octapeptide-3, Acetyl Hexapeptide-8, Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine, Palmitoyl Dipeptide-5 Diaminohydroxybutyrate, Laminaria Digitata Extract, Opuntia Ficus-Indica Stem Extract, Tocopherol, Caprylyl Glycol, Hexylene Glycol, Sodium Hyaluronate, Galactoarabinan, Schizophyllan, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Beta-Sitosterol, Lecithin, Hydrogenated Phosphatidylcholine, Lysolecithin, Carbomer, Xanthan Gum, Magnesium Chloride, Disodium EDTA, Phytic Acid, Maltodextrin, Squalene, Aminomethyl Propanol, Citric Acid, Phenoxyethanol, Ethylhexylglycerin, Sodium Benzoate, Potassium Sorbate.

(INCI per ZO packaging; ZO reformulates periodically — defer to the carton for the definitive list.)
For a routine matched to your specific skin — your goals, tolerance and existing products — take the two-minute Skincare Quiz.
Take the Skincare Quiz